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Lannan S, Donaldson K, Brown D, MacNee W: Effect of cigarette smoke and its condensates on alveolar epithelial cell damage in vitro. Kim HJ, Liu X, Wang H, Kohyama T, Kobayashi T, Wen FQ, Romberger DJ, Abe S, MacNee W, Rahman I, et al.: Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, MacNee W: Oxidant-mediated lung epithelial cell tolerance: the position of intracellular glutathione and nuclear factor-kappaB. The function of intracellular polyamines. Mulier B, Rahman I, Watchorn T, Donaldson K, MacNee W, Jeffery PK: Hydrogen peroxide-induced epithelial damage: the protective role of intracellular nonprotein thiols (NPSH). Rahman I, Li XY, Donaldson K, Harrison DJ, MacNee W: Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo below oxidative stress. Aarbiou J, Ertmann M, van Wetering S, van Noort P, Rook D, Rabe KF, Litvinov SV, van Krieken JH, de Boer WI, Hiemstra PS: Human neutrophil defensins induce lung epithelial cell proliferation in vitro. West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, Harris C, Belinsky S, Dennis PA: Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.


Upon entering the blood, nicotine immediately stimulates the adrenal glands to launch the hormone epinephrine (adrenaline). Cattaneo MG, Codignola A, Vicentini LM, Clementi F, Sher E: Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma. Cadham CJ, Sanchez-Romero LM, Fleischer NL, Mistry R, Hirschtick JL, Meza R, Levy DT. Sekhon HS, Wright JL, Churg A: Cigarette smoke causes fast cell proliferation in small airways and related pulmonary arteries. To understand this course of at a molecular degree, tissue samples from non-smoking and smoking mothers have been studied to determine whether or not active and/or passive cigarette smoke publicity impacts CTB expression of molecules that govern cellular responses to oxygen tension: the von Hippel-Lindau tumor suppressor protein (pVHL), hypoxia-inducible transcription factors (HIFs) and vascular endothelial growth factor-A (VEGF). Cells have been passaged weekly utilizing Trypsin Versene (Bio Whittaker, Walkersville, MD), and starved for development components by in a single day incubation in serum-free medium before publicity to CSC.


Takeyama K, Jung B, Shim JJ, Burgel PR, Dao-Pick T, Ueki IF, Protin U, Kroschel P, Nadel JA: Activation of epidermal development issue receptors is answerable for mucin synthesis induced by cigarette smoke. Shao MX, Nakanaga T, Nadel JA: Cigarette smoke induces MUC5AC mucin overproduction through tumor necrosis factor-alpha-changing enzyme in human airway epithelial (NCI-H292) cells. Dypbukt JM, Ankarcrona M, Burkitt M, Sjoholm A, Strom K, Orrenius S, Nicotera P: Different prooxidant levels stimulate development, set off apoptosis, or produce necrosis of insulin-secreting RINm5F cells. Kurie JM, Shin HJ, Lee JS, Morice RC, Ro JY, starbuzz electronic hookah Lippman SM, Hittelman WN, Yu R, Lee JJ, Hong WK: Increased epidermal progress issue receptor expression in metaplastic bronchial epithelium. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG: Transformation of mammalian cells by constitutively energetic MAP kinase kinase. Trichopoulos D, Mollo F, Tomatis L, Agapitos E, Delsedime L, Zavitsanos X, Kalandidi A, Katsouyanni K, Riboli E, Saracci R: Active and passive smoking and pathological indicators of lung most cancers risk in an autopsy study. The chatbot continues to be active as of June 2022, with over 1.Four million subscribers.